FIH-1 Disrupts an LRRK1/EGFR Complex to Positively Regulate Keratinocyte Migration
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چکیده
منابع مشابه
Cyclic AMP mediates keratinocyte directional migration in an electric field.
Re-epithelialization of wounded skin is necessary for wound closure and restoration of barrier function and requires directional keratinocyte migration towards the center of the wound. The electric field (EF) generated immediately upon wounding could be the earliest signal keratinocytes receive to initiate directional migration and healing. Keratinocytes express many beta2-adrenergic receptors ...
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Osteopontin (OPN) is a multifunctional protein involved in both innate immunity and adaptive immunity. However, the function of OPN, especially the intracellular form OPN (iOPN) on innate antiviral immune response remains elusive. Here, we demonstrated that iOPN is an essential positive regulator to protect the host from virus infection. OPN deficiency or knockdown significantly attenuated viru...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2014
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2014.08.014